Sleep deprivation significantly decreases activity in appetitive evaluation regions within the human brain and increases food purchasing the next day.
Sleep deprivation has been shown to reduce activity in appetitive evaluation regions within the human frontal cortex and insular cortex during food desirability choices. Functional magnetic resonance imaging (fMRI) was used to scan the brain of 23 healthy volunteers following both a normal night's sleep and a sleepless night. Activity in the frontal lobe, the region responsible for complex decision making, was impaired in the sleep-deprived brain while increased activity was observed in deeper brain centers which respond to rewards. Participants desired more high-calorie foods when they were sleep deprived. The findings suggest a brain mechanism by which sleep deprivation may influence the development of obesity.
Acute sleep deprivation has also been reported to increase food purchasing the following day. Sleep deprivation was associated with an increase in plasma ghrelin concentrations, a hormone responsible for increasing hunger, in 14 healthy volunteers. Sleep deprived individuals purchased significantly more calories and grams of food than they did after one night of sleep. The study suggests that acute sleep loss may influence food purchasing behavior.